Design and analysis of clinical trials :

000SB:610.724
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Chow, Shein-Chung. Design and analysis of clinical trials : concepts and methodologies / Shein-Chung Chow and Jen-Pei Liu. - 3rd ed. - New Jersey : John Wiley, c2014.
xii, 870 p. : ill. ; 26 cm. - (Wiley series in probability and statistics ) Content notes : 1. Introduction--
2. Basic statistical concepts--
3. Basic design considerations--
4. Randomization and blinding--
5. Designs for clinical trials--
6. Designs for cancer clinical trials--
7. Classification of clinical trials--
8. Analysis of continuous data--
9. Analysis of categorical data--
10. Censored data and interim analysis--
11. Sample size determination--
12. Issues in efficacy evaluation--
13. Safety assessment--
14. Biomarkers and targeted clinical trials--
15. Trials for evaluating accuracy of diagnostic devices--
16. Statistical methods in translational medicine--
17. Adaptive clinical trial designs--
18. Traditional Chinese medicine--
19. Preparation and implementation of a clinical protocol--
20. Data management of clinical trial--
References--
Appendix A--
Index.
9780470887653 (cloth) * Clinical trials - Methodology. Clinical trials - Statistical methods. * Liu, Jen-Pei. * Title * Series