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A pharmacology primer [electronic resource] : theory, applications, and methods / Terry Kenakin.

By: Kenakin, Terrence P.
Material type: TextTextPublisher: Amsterdam ; Boston : Elsevier Academic Press, c2006Edition: 2nd ed.Description: 1 online resource (xviii, 299 p.) : ill. (some col.), ports.ISBN: 0080465307 (electronic bk.); 9780080465302 (electronic bk.).Subject(s): Pharmacology | Drugs | Chemicals -- Physiological effect | Receptors, Drug -- physiology | Dose-Response Relationship, Drug | Pharmacology -- methods | Pharmacologie | M�edicaments | Produits chimiques -- Effets physiologiques | MEDICAL / Drug Guides | MEDICAL / Nursing / Pharmacology | MEDICAL / Pharmacology | MEDICAL / PharmacyGenre/Form: Electronic books.Additional physical formats: Print version:: Pharmacology primer.DDC classification: 615.1 Online resources: EBSCOhost
Contents:
What is Pharmacology? -- How Different Tissues Process Drug Response -- Drug Receptor Theory -- Pharmacological Assay Formats: Binding -- Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- Orthosteric Drug Antagonism -- Allosteric Drug Antagonism -- The Process of Drug Discovery -- Target- and System-based Strategies for Drug Discovery -- Hit to Drug: Lead Optimization -- Statistics and Experimental Design -- Selected Pharmacological Methods -- Glossary of Pharmacological Terms -- Appendices: -- Statistical Tables -- Mathematical Fitting Functions.
Summary: The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. *Over 30 new figures and tables *More human interest information to provide readers with historical facts on pharmacology research *New section on therapeutics to help identify diseaes and drug treatments *New section on new biological concepts relevant to pharmacological research (i.e., systems biology) *New study sections organized with ASPET and other international pharmacology organizations *New coverage of pharmacokinetics and drug disposition.
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The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. *Over 30 new figures and tables *More human interest information to provide readers with historical facts on pharmacology research *New section on therapeutics to help identify diseaes and drug treatments *New section on new biological concepts relevant to pharmacological research (i.e., systems biology) *New study sections organized with ASPET and other international pharmacology organizations *New coverage of pharmacokinetics and drug disposition.

What is Pharmacology? -- How Different Tissues Process Drug Response -- Drug Receptor Theory -- Pharmacological Assay Formats: Binding -- Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- Orthosteric Drug Antagonism -- Allosteric Drug Antagonism -- The Process of Drug Discovery -- Target- and System-based Strategies for Drug Discovery -- Hit to Drug: Lead Optimization -- Statistics and Experimental Design -- Selected Pharmacological Methods -- Glossary of Pharmacological Terms -- Appendices: -- Statistical Tables -- Mathematical Fitting Functions.

Includes bibliographical references and index.

Description based on print version record.

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A pharmacology primer by Kenakin, Terrence P. ©2006
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