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Randomization in clinical trials : theory and practice / William F. Rosenberger and John M. Lachin.

By: Contributor(s): Material type: TextTextSeries: Wiley series in probability and statisticsPublication details: New Jersey : John Wiley, c2016.Description: xvi, 253 p.: illustrations ; 25 cmISBN:
  • 9781118742242
Subject(s): DDC classification:
  • 000SB:615 23 R814
Contents:
1. Randomization and the clinical trial -- 2. Issues in the design of clinical trials -- 3. Randomization for balancing treatment assignments -- 4. The effects of unobserved covariates -- 5. Selection bias -- 6. Randomization as a basis for inference -- 7. Stratification -- 8. Restricted randomization in practice -- 9. Covariate-adaptive randomization -- 10. Response-adaptive randomization -- 11. Inference for response-adaptive randomization -- 12. Response-adaptive randomization in practice -- Author index -- Subject index.
Summary: This Second Edition features a unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications.
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Includes bibliographical references and indexes.

1. Randomization and the clinical trial --
2. Issues in the design of clinical trials --
3. Randomization for balancing treatment assignments --
4. The effects of unobserved covariates --
5. Selection bias --
6. Randomization as a basis for inference --
7. Stratification --
8. Restricted randomization in practice --
9. Covariate-adaptive randomization --
10. Response-adaptive randomization --
11. Inference for response-adaptive randomization --
12. Response-adaptive randomization in practice --
Author index --
Subject index.

This Second Edition features a unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications.

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