TY - BOOK AU - Atkinson,Anthony C. AU - Biswas,Atanu TI - Randomised response-adaptive designs in clinical trials T2 - Monographs on statistics and applied probability SN - 9781584886938 (hardcover : alk. paper) U1 - 000SB:615.50724 23 PY - 2014/// CY - Boca Raton PB - CRC Press KW - Clinical Trials as Topic KW - methods KW - Clinical Trials KW - Statistical Methods N1 - Includes bibliographical references (pages 299-318) and index; 1. Adaptive design : controversies and progress -- 2. Randomized balanced sequential treatment allocation -- 3. Response-adaptive designs for binary responses -- 4. Response-adaptive designs for continuous responses -- 5. Response-adaptive designs for longitudinal responses -- 6. Optimum biased-coin designs with covariates -- 7. Optimum response-adaptive designs with covariates -- 8. Optimal response-adaptive designs with constraints -- 9. Adaptive design : further important issues-- A Optimum design-- Bibliography-- Index N2 - Response-adaptive designs, which aim to reduce the number of patients receiving inferior treatments, are popular in Phase III clinical trials. This book provides an overview of the research in this area ER -