| 000 | 02270cam a2200277 a 4500 | ||
|---|---|---|---|
| 001 | 135767 | ||
| 003 | ISI Library, Kolkata | ||
| 005 | 20150526115225.0 | ||
| 008 | 120703s2014 njua b 001 0 eng | ||
| 020 | _a9780470887653 (cloth) | ||
| 040 | _aISI Library | ||
| 082 | 0 | 0 |
_a000SB:610.724 _223 _bC552 |
| 100 | 1 | _aChow, Shein-Chung. | |
| 245 | 1 | 0 |
_aDesign and analysis of clinical trials : _bconcepts and methodologies / _cShein-Chung Chow and Jen-Pei Liu. |
| 250 | _a3rd ed | ||
| 260 |
_aNew Jersey : _bJohn Wiley, _cc2014. |
||
| 300 |
_axii, 870 p. : _bill. ; _c26 cm. |
||
| 490 | 0 | _aWiley series in probability and statistics | |
| 504 | _aIncludes bibliographical references (p. 799-844) and index. | ||
| 505 | 8 | _a1. Introduction-- 2. Basic statistical concepts-- 3. Basic design considerations-- 4. Randomization and blinding-- 5. Designs for clinical trials-- 6. Designs for cancer clinical trials-- 7. Classification of clinical trials-- 8. Analysis of continuous data-- 9. Analysis of categorical data-- 10. Censored data and interim analysis-- 11. Sample size determination-- 12. Issues in efficacy evaluation-- 13. Safety assessment-- 14. Biomarkers and targeted clinical trials-- 15. Trials for evaluating accuracy of diagnostic devices-- 16. Statistical methods in translational medicine-- 17. Adaptive clinical trial designs-- 18. Traditional Chinese medicine-- 19. Preparation and implementation of a clinical protocol-- 20. Data management of clinical trial-- References-- Appendix A-- Index. | |
| 520 | _aPraise for the Second Edition: " ... a grand feast for biostatisticians. It stands ready to satisfy the appetite of any pharmaceutical scientist with a respectable statistical appetite."--Journal of Clinical Research Best Practices The Third Edition of Design and Analysis of Clinical Trials provides complete, comprehensive, and expanded coverage of recent health treatments and interventions. Featuring a unified presentation, the book provides a well-balanced summary of current regulatory requirements and recently developed statistical methods as well as. | ||
| 650 | 0 |
_aClinical trials _xMethodology. |
|
| 650 | 0 |
_aClinical trials _xStatistical methods. |
|
| 700 | 1 | _aLiu, Jen-Pei. | |
| 942 |
_2ddc _cBK |
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| 999 |
_c418723 _d418723 |
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