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020 _a9781402054686
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024 7 _a10.1007/978-1-4020-5468-6
_2doi
040 _aISI Library, Kolkata
050 4 _aQH323.5
050 4 _aQH324.2-324.25
072 7 _aPDE
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072 7 _aMAT003000
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072 7 _aPDE
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082 0 4 _a570.285
_223
245 1 0 _aSystems Biology
_h[electronic resource] :
_bInternational Research and Development /
_cedited by MARVIN CASSMAN, ADAM ARKIN, FRANK DOYLE, FUMIAKI KATAGIRI, DOUGLAS LAUFFENBURGER, CYNTHIA STOKES.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2007.
300 _aXVIII, 262 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aExecutive Summary and Introduction -- Data and Databases -- Network Inference -- Modeling and Network Organization -- Systems Biology in Plant Research -- Education, National Programs, and Infrastructure in Systems Biology.
520 _aSystems biology is defined for the purpose of this study as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. This involves a variety of approaches, such as the identification and validation of networks, the creation of appropriate datasets, the development of tools for data acquisition and software development, and the use of modeling and simulation software in close linkage with experiment. All of these are discussed in this volume. Of course, the definition becomes ambiguous at the margins, but at the core is the focus on networks, which makes it clear that the goal is to understand the operation of the systems, rather than the component parts. It was concluded that the U.S. is currently ahead of the rest of the world in systems biology, largely because of earlier investment by funding organizations and research institutions. This is reflected in a large number of active research groups, and educational programs, and a diverse and growing funding base. However, there is evidence of rapid development outside the U.S., much of it begun in the last two to three years. Overall, however, the picture is of an active field in the early stages of explosive growth. This volume is aimed at academic researchers, government research agency representatives and graduate students.
650 0 _aBioinformatics.
650 0 _aDevelopmental biology.
650 1 4 _aMathematical and Computational Biology.
_0http://scigraph.springernature.com/things/product-market-codes/M31000
650 2 4 _aBioinformatics.
_0http://scigraph.springernature.com/things/product-market-codes/L15001
650 2 4 _aDevelopmental Biology.
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700 1 _aCASSMAN, MARVIN.
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700 1 _aARKIN, ADAM.
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700 1 _aDOYLE, FRANK.
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700 1 _aKATAGIRI, FUMIAKI.
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700 1 _aLAUFFENBURGER, DOUGLAS.
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700 1 _aSTOKES, CYNTHIA.
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_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
_z9781402054679
856 4 0 _uhttps://doi.org/10.1007/978-1-4020-5468-6
912 _aZDB-2-SMA
942 _cEB
950 _aMathematics and Statistics (Springer-11649)
999 _c425440
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